Informazioni sulla sperimentazione dei farmaci

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Codice EUDRACT	Titolo/oggetto del contratto di sperimentazione	Promotore
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2022-001067-27	A multicenter, international, randomized, placebo controlled, double-blind, parallel group and event driven Phase 3 study of the oral FXIa inhibitor ...	Bayer Spa	Dettaglio
2016-002154-20	A multicenter, randomized, double-bind, active-controlled, parallelgroup Phase 3 study to evaluate the efficacy and safety of LCZ696 compared to ramipril ...	Novartis Farma S.p.A per Novartis Pharma AG	Dettaglio
2015-001564-19	A multicenter, randomized, open-label Phase 2 study evaluating the safety and efficacy of three different regimens of oral panobinostat in ...	Novartis Farma S.p.A per Novartis Pharma AG	Dettaglio
2021-005338-40	A Phase 1-2, Open-Label Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Activity of Tolinapant in Combination with Oral Decitabine/Cedazuridine ...	Astex Pharmaceuticals, Inc.	Dettaglio
2019-001545-41	A Phase 1/2A First in Human Study of the Menin-MLL (KMT2A) Inhibitor KO-539 in Patients with Relapsed or Refractory Acute ...	Kura Oncology, Inc.	Dettaglio
2019-004948-30	A Phase 2, Open-Label, Multicenter, Rollover Study to Provide Continued Treatment for Participants With Advanced Malignancies Previously Enrolled in Studies ...	Incyte Corporation	Dettaglio
2015-003447-19	A phase 3 Multicenter Open-label Study of Brigatinib (AP26113) versus Crizotinib in Patients with ALK-positive Advanced Lung Cancer	ARIAD Pharmaceuticals Inc. un’azienda interamente controllata da Takeda Pharmaceutical Company Limited	Dettaglio
2021-001234-20	A Phase 3 Open-Label, Randomized Study of Pirtobrutinib (LOXO-305) versus Bendamustine plus Rituximab in Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma ...	Loxo Oncology, Inc. 281 Tresser Boulevard Stamford, CT 06901	Dettaglio
2020-000241-14	A Phase 3 Randomized Study of Loncastuximab Tesirine Combined with Rituximab Versus Immunochemotherapy in Patients with Relapsed or Refractory Diffuse ...	ADC Therapeutics SA	Dettaglio
2017-000996-98	A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects with ...	CSL Behring LLC	Dettaglio
2020-002620-36	A Phase 3, open label, Multi-center, randomized study evaluating the efficacy of TAR 200 in combination with cetrelimab versus concurrentchemo-radiotherapy ...	Janssen Research & Development, LLC	Dettaglio
2022-502959-54	A phase 3, open label, randomized, multi-center study of DZD9008 versus Platinum-based doublet chemotherapy as first-line treatment for patients with ...	Dizal (Jiangsu) Pharmaceutical Co., Ltd	Dettaglio
2020-004506-64	A Phase 3, Open-Label, Multi-Center, Randomized Study Evaluating the Efficacy and Safety of TAR-200 in Combination with Cetrelimab Versus Intravesical ...	Janssen-Cilag SpA	Dettaglio
2020-004506-64	A Phase 3, Open-Label, Multi-Center, Randomized Study Evaluating the Efficacy and Safety of TAR-200 in Combination with Cetrelimab Versus Intravesical ...	Janssen-Cilag SpA	Dettaglio
2021-001825-33	A Phase 3, Open-Label, Randomized Study of Amivantamab and Lazertinib in Combination with Platinum-Based Chemotherapy Compared with Platinum-Based Chemotherapy in ...	Janssen-Cilag SpA	Dettaglio
2022-001012-26	A Phase 3, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of intravenous efzofitimod in patients with pulmonary sarcoidosis	aTyr Pharma, Inc.	Dettaglio
2019-003126-25	A Phase I/II, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics and Anti-tumor Efficacy of ZD9008 in Patients with ...	Dizal (Jiangsu) Pharmaceutical Co., Ltd	Dettaglio
2015-001998-40	A phase Ib/II study evaluating the safety and efficacy of obinutuzumab in combination with polatuzumab vedotin and venetoclax in patients ...	F.Hoffmann-La Roche Ltd	Dettaglio
2016-003703-62	A phase II study of metronomic chemotherapy in elderly non-fit patients (>65 years) with aggressive B-Cell lymphomas	Fondazione Italiana Linfomi ONLUS (FIL)	Dettaglio
MS100070_0119	A Phase II, Multicenter, Randomized, Open Label, Parallel-Arm, Umbrella Study of Avelumab (MSB0010718C) in Combination with Other Anti-Tumor Agents as ...	Merck KGaA	Dettaglio
2016-004359-57	A Phase III Study of BBI-608 plus nab-Paclitaxel whit Gemcitabine in Adult Patients with Metastatic Pancreatic Adenocarcinoma	Boston Biomedical Inc	Dettaglio
2017-004011-39	A phase III, multicenter, randomized, double blind, placebo-controlled study evaluating the efficacy and safety of canakinumab versus placebo as adjuvant ...	Novartis Farma S.p.A per Novartis Pharma AG	Dettaglio
2017-001664-37	A randomized phase 2 study comparing immunotherapy with chemotherapy in the treatment of elderly patients with advanced NSCLC	Istituto Nazionale per la Cura dei Tumori-Fondazione G.Pascale	Dettaglio
2015-001151-68	A randomized Phase III study to compare arsenic trioxide (ATO) combined to ATRA and idarubicin versus standard ATRA and anthracycLine-based ...	Università di Dresda	Dettaglio
2018-000367-83	A Randomized Phase III Trial of Platinum Chemotherapy plus Paclitaxel with Bevacizumab and Atezolizumab versus Platinum Chemotherapy plus Paclitaxel and ...	GEICO	Dettaglio

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Titolo/oggetto del contratto di sperimentazione
Codice EUDRACT
Promotore
Nome Unità Operativa
Principal investigator

W06 Informazioni sulle sperimentazioni dei farmaci (art.11, c.4bis, D.Lgs 211/200)